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September 2010
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Home arrow R & D arrow Research Areas

Research Areas

(A)  RESEARCH IN ZOONOTIC DISEASES
  • Development and establishment of early warning immunological and molecular based detection system for Avian Influenza (AI)

  • Development of HPAI-RT and Real-Time PCR for detection of AI virus, particularly subtypes H5 and H7

  • Development of polymerase chain reaction (PCR) and nucleotide sequencing to determine pathogenicity of avian influenzae virus

  • Determination of Bovine Spongiform Encephalopathy (BSE) risk in cattle in Malaysia

  • Establishment of ELISA rapid test for BSE

  • Epidemiology of Nipah Virus Disease:  The search for natural reservoir hosts

  • Development of competitive-ELISA for detection of Nipah virus

  • Development of monoclonal antibody for Nipah and Hendra virus

  • Genomic and proteomic analysis of Nipah virus isolates



(B)  RESEARCH IN POULTRY DISEASES
  • Development of PCR, nested PCR and antibody capture ELISA for the identification of certain specific disease of poultry

  • Characterisation of local avian reovirus isolates for diagnostic purposes and as candidate for development of a vaccine

  • Development of Newcastle Disease (ND) using recombinant  N-protein based ELISA

  • Functional analysis of a dual recombinant baculovirus-chicken anemia virus (CAV) proteins VP1 and VP2 - development of ELISA and vaccine

  • Epidemiology and economic impact of antibiotic resistant species of Enterococcus, Salmonella and Campylobacter on poultry production

  • Characterisation of local strains of Ornithobacterium rhinotracheale isolated from chickens

  • Studies on antibiotic resistance strains of Haemophilus paragallinarum

  • Coccidiosis in poultry - molecular based techniques for diagnosis, pathogenesis and control

  • Prevalence of Leucocytozoonosis in poultry  in Malaysia

(C)  RESEARCH IN RUMINANT DISEASES
  • The epidemiology of malignant catarrhal fever (MCF) in Malaysia: Development of diagnosis assay

  • Development of nested PCR, recombinant protein based-capture ELISA for bovine diarrhea (BVDV) and molecular characterisation of local isolates

  • Development of PCR, RT-PCR and Real-Time PCR for cattle, sheep, goat and horse disease

  • Development of herbal-based product NEEM (Azadirachta indica) as an alternative anti-parasitic chemotherapeutic for the control of gastrointestinal helminth parasites in small ruminants in Malaysia

  • Seroepidermiology of Neospora infection in cattle in Peninsular Malaysia

  • Characterisation of bovine viral diarrhea virus isolates and production of recombinant protein for the development of enzyme immunoassay

  • Development of an ELISA for detecting progesterone as indication of early pregnancy in cattle

  • Isolation of Pasteurella multocida from pharyngeal lymph nodes of  slaughtered cattle and buffalo for molecular characterisation

  • Establishment of rapid detection methods for Mycobacterium spp. from clinical specimens

  • Prevalence of  protozoan diseases in cattle - Babesia, Theileria and Trypanosoma

  • Anthelmintic resistance studies in small ruminants - use of  FECRT and LDA for diagnosis

  • Novel approaches to worm control  in sheep and goats in Malaysia - FAMACHA, RRG, MUMB, Biological control



(D)  RESEARCH IN DISEASES OF OTHER SPECIES
  • Development of rapid detection technique for Strangles in horses

  • Development of conventional and molecular based techniques (PCR) for the diagnosis of viral diseases of cultured fish and shellfish

  • Screening for piroplasmosis, surra and dourine in equines

  • Normal blood values in horses

  • Normal blood parameters of primates (orang utan)

  • Screening of wildlife for GIT helminths (orang utan)


(E)  RESEARCH INTO DEVELOPMENT OF BIOLOGICS AND VACCINES
  • Development of sheep and goat Pasteurellosis vaccine

  • Development of Reovirus vaccine for chickens

  • Commercial production of a local live Infectious Bronchitis (IB nephropathogenic strain) vaccine

  • Development of H5N2 Avian Influenzae killed vaccine
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